Mammalian cells of all types disgorge prostaglandins at the slightest provocation, but the tissue content of prostaglandins is very low compared with the release. – John Vane
It seems to me that the novel as a medium has a very low signal-to-noise ratio. By which I mean: there are a lot of novels published, but the vast majority of them don’t represent major contributions to the medium. – Lev Grossman
