Had Lydia’s marriage been concluded on the most honourable terms, it was not to be supposed that Mr. Darcy would connect himself with a family where, to every other objection would now be added, an alliance and relationship of the nearest kind with the man whom he so justly scorned.

– Jane Austen

Pride and Prejudice, Chapter 50. Elizabeth is concerned that Lydia’s marriage to Wickham will push Darcy further away from her. She cannot see him wanting to connect with a family that has made an alliance with the man he rightly scorned. To Elizabeth, she and Darcy appear even more separated now by Lydia’s marriage.