He was the cause, his pride and caprice were the cause, of all that Jane had suffered, and still continued to suffer. He had ruined for a while every hope of happiness for the most affectionate, generous heart in the world; and no one could say how lasting an evil he might have inflicted.
– Jane Austen
Pride and Prejudice, Chapter 33. Elizabeth lays the blame for the romantic breakup of Charles Bingley and her sister Jane entirely at the feet of Mr. Darcy and his pride. By intervening to stop their marriage, Darcy ruined the hope of happiness for the most loving and generous heart in the world, she believes. Elizabeth clearly loves Jane very much and is very upset that Darcy would do such a thing.