Lennie said, “George.”
“Yeah?”
“I done another bad thing.”
“It don’t make no difference,” George said, and he fell silent again.

– John Steinbeck

Of Mice and Men, Chapter 6. Lennie is afraid that George will be angry at him for killing Curley’s wife and may leave him. But his friend appears strangely calm and quiet. For George is crushed, he knows his dreams are shattered and he can’t get Lennie out of this one.