Thus spoke my prophetic soul, as torn by remorse, horror, and despair, I beheld those I loved spend vain sorrow upon the graves of William and Justine, the first hapless victims to my unhallowed arts.

– Mary Shelley

Frankenstein, Chapter 8. Victor is filled with the self-realization that he has created a monster, who has killed his brother, caused the execution of Justine, and may be the cause of further deaths.