You lack the season of all natures, sleep.

– William Shakespeare

Macbeth, Act 3, Scene 4. At the end of this scene in which Macbeth hallucinates the ghost of Banquo at his banquet, Lady Macbeth attributes his behavior to lack of sleep. There is a double irony in her words. The audience knows that Macbeth will never sleep properly again since killing King Duncan. Also later in the play it is Lady Macbeth who has sleep problems, she sleepwalks and talks in her sleep and needs a light near her because of fear of the dark.